in reference to:
Since 2005 it has become evident that a good amount of development in open chemical information is driven by the demands of neighbouring scientific fields. In many areas in biology, for example, the importance of small molecules and their interactions and reactions in biological systems has been realised. In fact, one of the first free and open databases and ontologies of small molecules was created as a resource about chemical structure and nomenclature by biologists .
This is test annotation.